Ethylene → 1-(2-Bromoethyl)-3,5-dimethyl Adamantane
反応式
Br[C:2]12[CH2:11][C:6]3([CH3:12])[CH2:7][CH:8]([CH2:10][C:4]([CH3:13])([CH2:5]3)[CH2:3]1)[CH2:9]2.[Br-:14].[Al+3].[Br-].[Br-].[CH2:18]=[CH2:19]>CCCCCC>[Br:14][CH2:18][CH2:19][C:8]12[CH2:10][C:4]3([CH3:13])[CH2:3][CH:2]([CH2:11][C:6]([CH3:12])([CH2:5]3)[CH2:7]1)[CH2:9]2参加物
5
実験手順
Mix 1.4 mol of 1-bromo-3,5-dimethyl adamantane (I) in hexane with 0.6 mol of aluminum bromide at -75° C. Subsequently, pass ethylene through the solution for 20-30 minutes, stir for 5 min., and pour the reaction mixture onto ice water. Extract with ether, dry the organic phase and evaporate to dryness. Recrystallize the residue from methanol. (Yield: 48%).
後処理
- customfor 20-30 minutes
- additionpour the reaction mixture onto ice water
- extractionExtract with ether
- customdry the organic phase
- customevaporate to dryness
- customRecrystallize the residue from methanol
出典と根拠
- ORDレコード
- ord-8ea37ed7204243fe814166548c4d8d15
- 出典データセット
- uspto-grants-1991_10
- 特許番号
- US05061703
反応ノート
読み込み中…