3-Phenoxybenzaldehyde → 5,5-Dimethyl-2-(3-phenoxyphenyl)-3-(4-phenylbutyl)-4-thiazolidinone

HRID 346249

反応式

HRID 346249 の反応式
[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH:11]=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[SH:16][C:17]([CH3:22])([CH3:21])[C:18](O)=[O:19].[C:23]1([CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>C1C=CC=CC=1>[CH3:21][C:17]1([CH3:22])[S:16][CH:11]([C:10]2[CH:13]=[CH:14][CH:15]=[C:8]([O:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH:9]=2)[N:33]([CH2:32][CH2:31][CH2:30][CH2:29][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:18]1=[O:19]

参加物

5

反応物 3

HCID 382843-PhenoxybenzaldehydeHCID 784212-Mercapto-2-methylpropanoic acidHCID 83242Benzenebutanamine

生成物 1

HCID 199906025,5-Dimethyl-2-(3-phenoxyphenyl)-3-(4-phenylbutyl)-4-thiazolidinone

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

Using the procedures of Example 5, the title compound was prepared as a light yellow viscous oil (8.4 g, 65%) from 5.9 g (0.030 mole) of 3-phenoxybenzaldehyde (Fluka), 3.6 g (0.030 mole) of 2-mercapto-2-methylpropionic acid, and 4.6 g (0.030 mole) of 4-phenylbutylamine after refluxing in 250 ml of benzene overnight.

出典と根拠

ORDレコード
ord-79c0bbcc9ca8426eb94a9eff610b6370
出典データセット
uspto-grants-1991_10
特許番号
US05061720

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