Sorbitol → Sorbitol hydroxypropyltrimethylammonium chloride

HRID 347614

反応式

HRID 347614 の反応式
[OH:1][CH2:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[Cl-].[Cl:14]CC(O)[CH2:17][N+:18](C)([CH3:20])[CH3:19].[OH-].[Na+]>>[Cl-:14].[OH:1][CH2:2][CH2:3][CH2:5][N+:18]([CH3:20])([CH3:19])[CH3:17].[OH:12][CH2:11][C@@H:9]([C@H:7]([C@@H:5]([C@@H:3]([CH2:2][OH:1])[OH:4])[OH:6])[OH:8])[OH:10]

参加物

4

反応物 3

HCID 5780Sorbitol2 回HCID 14798Sodium HydroxideHCID 18732(3-Chloro-2-hydroxypropyl)trimethylammonium chloride

生成物 1

HCID 86604622Sorbitol hydroxypropyltrimethylammonium chloride

実験手順

Herein is provided a synthesis procedure for the chloride salt of hydroxypropyltrimonium sorbitol (also referred to as ‘Sorbitol Monoquat’). A round bottom 250 ml flask was fitted with a mechanical stirrer. Into the flask was charged a mixture of sorbitol (10 g, 55.0 mmol) and 3-chloro-2-hydroxypropyl trimethylammonium chloride (Quat 188®) (15 ml, 55.0 mmol). One molar sodium hydroxide (55.0 ml, 55.0 mmol) was then added to the charged mixture. The resultant solution was stirred at room temperature for 18 hours. Water was then removed under reduced pressure at 50° C. yielding a heterogeneous colorless syrup. Filtration through glass wool afforded sorbitol hydroxypropyltrimethylammonium chloride as a homogeneous clear syrup: m/z (ESI; M+−Cl−) 298.

後処理

  1. customHerein is provided
  2. customA round bottom 250 ml flask was fitted with a mechanical stirrer
  3. additionInto the flask was charged
  4. customWater was then removed under reduced pressure at 50° C.
  5. customyielding a heterogeneous colorless syrup
  6. filtrationFiltration through glass wool

出典と根拠

ORDレコード
ord-ba2eb52636ab420ebb67a158eb09807f
出典データセット
uspto-grants-2007_02
特許番号
US07176172B2

関連ノート

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