Acetic Anhydride → HCID 21920974、化合物

HRID 349588

反応式

HRID 349588 の反応式
[Cl-].[Cl-].[Cl-].[Al+3].[C:5](OC(=O)C)(=[O:7])[CH3:6].[CH2:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH:13]1[NH:21][C:22](=[O:30])[C:23]1[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=1>ClCCCl>[C:5]([C:18]1[CH:19]=[C:20]2[C:15](=[CH:16][CH:17]=1)[CH2:14][CH:13]([NH:21][C:22](=[O:30])[C:23]1[CH:24]=[CH:25][C:26]([F:29])=[CH:27][CH:28]=1)[CH2:12]2)(=[O:7])[CH3:6]

参加物

5

反応物 3

HCID 7918Acetic AnhydrideHCID 6451240Aluminum(III) ChlorideHCID 10131276Ave-9488

生成物 1

HCID 21920974HCID 21920974、化合物

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

2.87 g (21.6 mmol) aluminum trichloride were suspended in 10 ml 1,2-dichloroethane, 500 mg (4.9 mmol) acetic anhydride and 1.0 g N-(indan-2-yl)-4-fluoro-benzamide added, and the whole was stirred for 2 h at RT. The resulting mixture was poured onto ice water/HCl, extracted with dichloromethane, the organic phase was dried with Na2SO4 and evaporated.

後処理

  1. additionThe resulting mixture was poured onto ice water/HCl
  2. extractionextracted with dichloromethane
  3. dry with materialthe organic phase was dried with Na2SO4
  4. customevaporated

出典と根拠

ORDレコード
ord-12d8dcb51e2c4376b2cab1e7072141cf
出典データセット
uspto-grants-2007_02
特許番号
US07179839B2

関連ノート

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