Hydrochloric Acid → (1-Chloropropyl)benzene
反応式
[C:1]1([CH:7](O)[CH2:8][CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:11]>O>[Cl:11][CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:8][CH3:9]参加物
4
実験手順
13.6 g (0.1 mole) of 1-phenylpropan-1-ol are taken up in petroleum ether and are reacted at -20° C. with hydrochloric acid until the precipitation of water is terminated. Subsequently, the organic phase is washed neutral with water, dried (sodium sulfate) and the petroleum ether removed in a vacuum. The bright yellow, thermolabile oil is used without further purification. The oil has an Rf of 0.8 (CH2Cl2) and is attained in a yield of 13.1 g (85%).
後処理
- customis terminated
- washSubsequently, the organic phase is washed neutral with water
- dry with materialdried (sodium sulfate)
- customthe petroleum ether removed in a vacuum
- customThe bright yellow, thermolabile oil is used without further purification
出典と根拠
- ORDレコード
- ord-dcd316a38b4f4ea7a34c064d42946357
- 出典データセット
- uspto-grants-1988_08
- 特許番号
- US04764533
反応ノート
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