Potassium Iodide → 2-Allyl-3,4-dichlorophenol

HRID 34966

反応式

HRID 34966 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:10](Br)[CH:11]=[CH2:12].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>C(C(C)=O)C>[CH2:12]([C:3]1[C:2]([Cl:1])=[C:7]([Cl:8])[CH:6]=[CH:5][C:4]=1[OH:9])[CH:11]=[CH2:10]

参加物

6

反応物 4

HCID 4875Potassium IodideHCID 72583,4-DichlorophenolHCID 7841Allyl bromideHCID 11430Potassium Carbonate

生成物 1

HCID 142330452-Allyl-3,4-dichlorophenol

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

反応条件

温度
200 °C

実験手順

A solution of 100 g. of 3,4-dichlorophenol, 50 ml. of allyl bromide, 84 g. of potassium carbonate, and 1.0 g. of potassium iodide in 500 ml. of methyl ethyl ketone was allowed to reflux overnight. The solution was then cooled, filtered, and evaporated to dryness. The residue was then heated at 200° C. for approximately four hours. NMR analysis indicated that the 113.6 g. of remaining material was primarily the desired 2-allyl-3,4-dichlorophenol.

後処理

  1. temperatureto reflux overnight
  2. temperatureThe solution was then cooled
  3. filtrationfiltered
  4. customevaporated to dryness

出典と根拠

ORDレコード
ord-99355c9dac3a4ade8fb9d00ba4a791bd
出典データセット
uspto-grants-1988_08
特許番号
US04764521

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