Potassium Iodide → 2-Allyl-3,4-dichlorophenol
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:10](Br)[CH:11]=[CH2:12].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>C(C(C)=O)C>[CH2:12]([C:3]1[C:2]([Cl:1])=[C:7]([Cl:8])[CH:6]=[CH:5][C:4]=1[OH:9])[CH:11]=[CH2:10]参加物
6
反応条件
- 温度
- 200 °C
実験手順
A solution of 100 g. of 3,4-dichlorophenol, 50 ml. of allyl bromide, 84 g. of potassium carbonate, and 1.0 g. of potassium iodide in 500 ml. of methyl ethyl ketone was allowed to reflux overnight. The solution was then cooled, filtered, and evaporated to dryness. The residue was then heated at 200° C. for approximately four hours. NMR analysis indicated that the 113.6 g. of remaining material was primarily the desired 2-allyl-3,4-dichlorophenol.
後処理
- temperatureto reflux overnight
- temperatureThe solution was then cooled
- filtrationfiltered
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-99355c9dac3a4ade8fb9d00ba4a791bd
- 出典データセット
- uspto-grants-1988_08
- 特許番号
- US04764521
反応ノート
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