Dimethyl N-cyanodithioiminocarbonate → HCID 178503919、化合物

HRID 35052

反応式

HRID 35052 の反応式
[CH3:1][S:2][C:3](SC)=[N:4][C:5]#[N:6].[N:9]1([CH2:14][C:15]2[CH:16]=[C:17]([CH:23]=[CH:24][CH:25]=2)[O:18][CH2:19][CH2:20][CH2:21][NH2:22])[CH2:13][CH2:12][CH2:11][CH2:10]1>C(OCC)(=O)C>[C:5]([N:4]=[C:3]([S:2][CH3:1])[NH:22][CH2:21][CH2:20][CH2:19][O:18][C:17]1[CH:23]=[CH:24][CH:25]=[C:15]([CH2:14][N:9]2[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:16]=1)#[N:6]

参加物

4

反応物 2

HCID 66289Dimethyl N-cyanodithioiminocarbonateHCID 127974543-{3-[(Pyrrolidin-1-yl)methyl]phenoxy}propan-1-amine

生成物 1

HCID 178503919HCID 178503919、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

A solution of N-cyano-carbonimidodithioic acid dimethyl ester (5 g) in ethyl acetate (50 ml) was added to a solution of 3-[3-(1-pyrrolidinylmethyl)phenoxy]propanamine in ethyl acetate (60 ml). The reaction mixture was stirred at room temperature for 1 hr to give the title compound as an off-white solid m.p. 107°-108.5° (7.45 g). TLC silica; ethyl acetate: isopropanol:water:0.88 ammonia (25:15:8:2) single spot Rf 0.7.

出典と根拠

ORDレコード
ord-8e99aae1d1e04736be34c3bafe85fee5
出典データセット
uspto-grants-1988_08
特許番号
US04764612

関連ノート

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