Cornforth reagent → N-(2-formyl-4-methoxyphenyl)formamide

反応式

[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[NH:11][CH:12]=[O:13].[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[NH+]1C=CC=CC=1.[NH+]1C=CC=CC=1>>[CH:2]([C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[NH:11][CH:12]=[O:13])=[O:1]

参加物

反応物 2

HCID 2724130Cornforth reagent

HCID 21088390N-(2-hydroxymethyl-4-methoxyphenyl)formamide

生成物 1

HCID 21088389N-(2-formyl-4-methoxyphenyl)formamide

実験手順

5.00 g of the product from stage 2 were oxidised with pyridinium dichromate as described in Example 1, stage 2, 3.62 g (72% of theory) of the title compound being obtained.

出典と根拠

ORDレコード: ord-248f6d347b154ef0822781c21980ba25
出典データセット: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07183274B2

反応ノート

読み込み中…