Hydrochloric Acid → 3-Hydroxy-6-methoxypicolinic acid
反応式
[OH:1][C:2]1[C:3]([C:10]([O:12]C)=[O:11])=[N:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1.[OH-].[Na+].Cl>CO>[OH:1][C:2]1[C:3]([C:10]([OH:12])=[O:11])=[N:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1参加物
5
実験手順
Methyl 3-hydroxy-6-methoxypicolinate (80 mg) was dissolved in 4 ml of methanol. A 1 N aqueous sodium hydroxide solution (2 ml) was added to the solution, and a reaction was allowed to proceed at room temperature for 3 hr. The reaction solution was adjusted to pH 3 by the addition of 1 N hydrochloric acid. The precipitate was collected by filtration to give 56 mg (yield 76%) of the title compound.
後処理
- filtrationThe precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-3aa52d32650d45ef9ee35da5a67c7020
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07183278B1
反応ノート
読み込み中…