Hydrochloric Acid → 3-Benzyloxy-4,6-dimethoxypicolinic acid
反応式
[CH2:1]([O:8][C:9]1[C:10]([C:19]([O:21]C)=[O:20])=[N:11][C:12]([O:17][CH3:18])=[CH:13][C:14]=1[O:15][CH3:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+].Cl>CO>[CH2:1]([O:8][C:9]1[C:10]([C:19]([OH:21])=[O:20])=[N:11][C:12]([O:17][CH3:18])=[CH:13][C:14]=1[O:15][CH3:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
5
実験手順
Methyl 3-benzyloxy-4,6-dimethoxypicolinate (33 mg) was dissolved in 2 ml of methanol. A 1 N aqueous sodium hydroxide solution (0.54 ml) was added to the solution, and a reaction was allowed to proceed at room temperature for 4 hr. The reaction solution was neutralized with 1 N hydrochloric acid, and was then concentrated under the reduced pressure to give the title compound.
後処理
- concentrationwas then concentrated under the reduced pressure
出典と根拠
- ORDレコード
- ord-5a090a44df994585b500c776aab7e043
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07183278B1
反応ノート
読み込み中…