Tributylstannane → {1-[4-(Benzyloxy)phenyl]ethenyl}(tributyl)stannane

HRID 351433

反応式

HRID 351433 の反応式
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]#[CH:16])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:17][CH2:18][CH2:19][CH2:20][SnH:21]([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:22][CH2:23][CH2:24][CH3:25]>C1COCC1>[CH2:26]([Sn:21]([CH2:20][CH2:19][CH2:18][CH3:17])([CH2:22][CH2:23][CH2:24][CH3:25])[C:15]([C:12]1[CH:11]=[CH:10][C:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:14][CH:13]=1)=[CH2:16])[CH2:27][CH2:28][CH3:29]

参加物

4

反応物 2

HCID 5948TributylstannaneHCID 14903234'-Benzyloxyphenyl acetylene

生成物 1

HCID 18436367{1-[4-(Benzyloxy)phenyl]ethenyl}(tributyl)stannane

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

1-benzyloxy-4-ethynyl-benzene (70 g, 0.3365 mol), Bu3SnH (59 mL, 0.3365 mol) and Ph(PP3)2Cl2 (120 mg, 0.1718 mmol) were stirred in THF (500 mL) at 25° C. for 16 h and then refluxed for 1 h. The resulting solution was concentrated and then purified on SiO2 (2% ˜5% ethyl acetate/hexane) to yield tributyl-[1-(4-benzyloxy-phenyl)-vinyl]-stannane.

後処理

  1. temperaturerefluxed for 1 h
  2. concentrationThe resulting solution was concentrated
  3. custompurified on SiO2 (2% ˜5% ethyl acetate/hexane)

出典と根拠

ORDレコード
ord-548b48d2ddeb4a00adf7671038cb8c9d
出典データセット
uspto-grants-2007_02
特許番号
US07183445B2

関連ノート

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