Ethyl methanesulfonylacetate → Ethyl 3-dimethylamino-2-methylsulphonylacrylate
反応式
[CH3:1][S:2]([CH2:5][C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:4])=[O:3].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[CH3:13][N:14]([CH3:16])[CH:15]=[C:5]([S:2]([CH3:1])(=[O:4])=[O:3])[C:6]([O:8][CH2:9][CH3:10])=[O:7]参加物
3
反応条件
- 温度
- 85 °C
実験手順
6.65 g (40 mmol) of ethyl methanesulphonylacetate and 5.72 g (48 mmol) of N,N-dimethylformamide dimethyl acetal are admixed and heated at 85° C. overnight. The solution is concentrated using a rotary evaporator, and the solid is comminuted with cyclohexane and filtered off with suction.
後処理
- concentrationThe solution is concentrated
- customa rotary evaporator
- customthe solid is comminuted with cyclohexane
- filtrationfiltered off with suction
出典と根拠
- ORDレコード
- ord-d5b98d3c965f4e9796d425aac5851886
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06743798B1
反応ノート
読み込み中…