Acetyl chloride → 1-(6-Bromonaphthalen-2-yl)ethanone

HRID 35189

反応式

HRID 35189 の反応式
[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[C:12](Cl)(=[O:14])[CH3:13].[Cl-].[Al+3].[Cl-].[Cl-]>[N+](C1C=CC=CC=1)([O-])=O>[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12](=[O:14])[CH3:13])[CH:8]=2)[CH:3]=1

参加物

5

反応物 3

HCID 6367Acetyl chlorideHCID 113722-BromonaphthaleneHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 124330821-(6-Bromonaphthalen-2-yl)ethanone

試薬・触媒・溶媒 1

HCID 7416Nitrobenzene溶媒

反応条件

温度
100 °C

実験手順

A mixture of 41.4 g of 2-bromonaphthalene, 15.7 g of acetyl chloride and 28 g of aluminum chloride in 250 ml of nitrobenzene was stirred at 100° C. for 4 hours. The reaction mixture was poured onto ice water and the resulting solid filtered off, washed with water and distilled under reduced pressure. The distillate was recrystallized from hexane to yield 2-bromo-6-acetylnaphthalene.

後処理

  1. additionThe reaction mixture was poured onto ice water
  2. filtrationthe resulting solid filtered off
  3. washwashed with water
  4. distillationdistilled under reduced pressure
  5. customThe distillate was recrystallized from hexane

出典と根拠

ORDレコード
ord-6b8ce0e0912b4f5087e0b932e9425f44
出典データセット
uspto-grants-1988_08
特許番号
US04766127

関連ノート

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