Acetyl chloride → 1-(6-Bromonaphthalen-2-yl)ethanone
反応式
[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[C:12](Cl)(=[O:14])[CH3:13].[Cl-].[Al+3].[Cl-].[Cl-]>[N+](C1C=CC=CC=1)([O-])=O>[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12](=[O:14])[CH3:13])[CH:8]=2)[CH:3]=1参加物
5
反応条件
- 温度
- 100 °C
実験手順
A mixture of 41.4 g of 2-bromonaphthalene, 15.7 g of acetyl chloride and 28 g of aluminum chloride in 250 ml of nitrobenzene was stirred at 100° C. for 4 hours. The reaction mixture was poured onto ice water and the resulting solid filtered off, washed with water and distilled under reduced pressure. The distillate was recrystallized from hexane to yield 2-bromo-6-acetylnaphthalene.
後処理
- additionThe reaction mixture was poured onto ice water
- filtrationthe resulting solid filtered off
- washwashed with water
- distillationdistilled under reduced pressure
- customThe distillate was recrystallized from hexane
出典と根拠
- ORDレコード
- ord-6b8ce0e0912b4f5087e0b932e9425f44
- 出典データセット
- uspto-grants-1988_08
- 特許番号
- US04766127
反応ノート
読み込み中…