Sodium Carbonate → HCID 15612244、化合物

HRID 35194

反応式

HRID 35194 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:18]4([CH3:23])OCC[O:19]4)[CH:14]=3)[CH:9]=2)[CH:2]=1.C(=O)([O-])[O-].[Na+].[Na+]>Cl>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:18](=[O:19])[CH3:23])[CH:14]=3)[CH:9]=2)[CH:2]=1

参加物

4

反応物 2

HCID 10340Sodium CarbonateHCID 156122432-(3-Pyridylmethyl)-6-(2-methyl-1,3-dioxolan-2-yl)naphthalene

生成物 1

HCID 15612244HCID 15612244、化合物収率 101.3%

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

A solution of 150 mg of 2-(3-pyridylmethyl)-6-(2-methyl-1,3-dioxolan-2-yl)naphthalene in 15 ml of 1N hydrochloric acid was allowed to stand for 3 hours at room temperature. The solution was neutralized with sodium carbonate and extracted with methylene chloride. The organic layer was dried over sodium sulfate and the solvent removed under reduced pressure to give 130 mg of 2-(3-pyridylmethyl)-6-acetylnaphthalene as an oil.

後処理

  1. extractionextracted with methylene chloride
  2. dry with materialThe organic layer was dried over sodium sulfate
  3. customthe solvent removed under reduced pressure

出典と根拠

ORDレコード
ord-d087129627ad4ec4a8be14aecff590ba
出典データセット
uspto-grants-1988_08
特許番号
US04766127

関連ノート

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