Lauric Acid → N-(2-Methoxy-5-pyridyl)-cyclopropane carboxamide dodecanoic acid salt

HRID 35206

反応式

HRID 35206 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]([CH:12]2[CH2:14][CH2:13]2)=[O:11])=[CH:5][N:4]=1.[C:15]([OH:28])(=[O:27])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>CC(C)=O>[C:15]([OH:28])(=[O:27])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]([CH:12]2[CH2:14][CH2:13]2)=[O:11])=[CH:5][N:4]=1

参加物

4

反応物 2

HCID 3893Lauric AcidHCID 86308N-(6-methoxypyridin-3-yl)cyclopropanecarboxamide

生成物 1

HCID 14304482N-(2-Methoxy-5-pyridyl)-cyclopropane carboxamide dodecanoic acid salt

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Three grams (0.016 mole) of the compound of Example 1 was dissolved in 100 ml of acetone in a 300 ml, one-neck, round-bottom flask by swirling. 3.2 g (0.016 mole) dodecanoic acid was added which went into solution. The resulting solution was evaporated on a rotary evaporator, yielding 6.2 g, of a white solid having a melting point of 92°-96° C., which was identified by nuclear magnetic resonance spectroscopy as the title compound. This compound will be known as Compound 7.

後処理

  1. customThe resulting solution was evaporated on a rotary evaporator
  2. customyielding 6.2 g

出典と根拠

ORDレコード
ord-e933d83f36084de3b604fe6075716b29
出典データセット
uspto-grants-1988_08
特許番号
US04766134

関連ノート

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