Allyl bromide → 2-Allyloxy-4-methoxy-benzaldehyde
反応式
[OH:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[CH2:12](Br)[CH:13]=[CH2:14].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:14]([O:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][C:3]=1[CH:4]=[O:5])[CH:13]=[CH2:12]参加物
5
実験手順
To a solution of 100 g of 2-hydroxy-4-methoxybenzaldehyde in 2 liters of acetone add 79.5 ml of allyl bromide and then, gradually, 272 g of potassium carbonate. Heat at reflux for 4 hours and then filter; concentrate the filtrate in vacuo, take up the residue in 1 liter of dichloromethane and wash the solution with 1N sodium hydroxide solution and then with saturated sodium chloride solution. Dry over magnesium sulphate and concentrate in vacuo.
後処理
- temperatureHeat
- temperatureat reflux for 4 hours
- filtrationfilter
- concentrationconcentrate the filtrate in vacuo
- washwash the solution with 1N sodium hydroxide solution
- dry with materialDry over magnesium sulphate
- concentrationconcentrate in vacuo
出典と根拠
- ORDレコード
- ord-cf0ee0ed87244302bbe261a0fb02db05
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06747032B2
反応ノート
読み込み中…