Hydrochloric Acid → HCID 20735499、化合物

HRID 353220ノート

反応式

HRID 353220 の反応式
C[S:2][C:3](=S)[O:4][CH:5]([CH3:7])[CH3:6].[C:9]([C:12]1[O:13][CH:14]=[CH:15][CH:16]=1)(=[O:11])[CH3:10].CC(C)([O-])C.[K+].Cl>C(O)(C)(C)C>[O:13]1[CH:14]=[CH:15][CH:16]=[C:12]1[C:9](=[O:11])[CH2:10][C:3](=[S:2])[O:4][CH:5]([CH3:7])[CH3:6]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 145052-AcetylfuranHCID 118783Carbonodithioic acid, S-methyl O-(1-methylethyl) esterHCID 23665647Potassium tert-butoxide

生成物 1

HCID 20735499HCID 20735499、化合物収率 37.3%

試薬・触媒・溶媒 1

HCID 6386tert-Butanol溶媒

実験手順

A mixture of isopropyl (methylsulfanyl)methanethioate (7.0 g, 46.7 mmol), 2-acetyl furan (5.14 g, 46.7 mmol), potassium t-butoxide (10.5 g, 93.5 mmol) and t-butanol (35 mL) was stirred overnight at room temperature. Ice was added to the reaction solution, followed by acidifying with 5 N hydrochloric acid. The solid was collected by filtration and washed with water, to give the title compound (3.7 g, 37%).

後処理

  1. additionIce was added to the reaction solution
  2. filtrationThe solid was collected by filtration
  3. washwashed with water

出典と根拠

ORDレコード
ord-2f53dca9c6d44218ba3fe382a5b992a3
出典データセット
uspto-grants-2004_06
特許番号
US06750232B2

反応ノート

読み込み中…