Butylamine → N-(Quinoxalin-6-ylmethyl)butan-1-amine

HRID 353324ノート

反応式

HRID 353324 の反応式
Br[CH2:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][CH:7]=[N:6]2.[CH2:13]([NH2:17])[CH2:14][CH2:15][CH3:16]>>[CH2:13]([NH:17][CH2:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][CH:7]=[N:6]2)[CH2:14][CH2:15][CH3:16]

参加物

3

実験手順

Example 10 shows that some organic solvent-soluble nucleophiles (alkylamines, for example) can readily react with 6-bromomethyl-quinoxaline because the compound is completely soluble in the organic phase. Example 10 shows that 6-bromomethyl-quinoxaline completely reacted with n-butylamine in few minutes at room temperature to give 6-n-butylaminomethyl-quinoxaline. In this example, n-butylamine acted as both the nucleophile and the solvent.

出典と根拠

ORDレコード
ord-ae7b1c0a9c044e1dabbaed12df37cce2
出典データセット
uspto-grants-2004_06
特許番号
US06750343B2

反応ノート

読み込み中…