Cyclohexaneacetic acid → Cyclohexylacetyl chloride

HRID 35372

反応式

HRID 35372 の反応式
[CH:1]1([CH2:7][C:8]([OH:10])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:13]>>[CH:1]1([CH2:7][C:8]([Cl:13])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

3

反応物 2

HCID 21363Cyclohexaneacetic acidHCID 24386Thionyl Chloride

生成物 1

HCID 2757989Cyclohexylacetyl chloride

実験手順

Cyclohexyl acetic acid (2.5 g; 0.02 moles) was mixed with SOCl2 (3.7 cc; 0.05 moles) and the resulting solution was kept at 80° C. for 1.5 hours. The mixture was concentrated under vacuum and some washings were carried out with anhydrous toluene to remove SOCl2. The mixture was then dried under vacuum and the title product was obtained as a raw material which was used as such in the next step (b).

後処理

  1. concentrationThe mixture was concentrated under vacuum
  2. customto remove SOCl2
  3. customThe mixture was then dried under vacuum

出典と根拠

ORDレコード
ord-469fa4391bba411b95e3dae68edade96
出典データセット
uspto-grants-1988_08
特許番号
US04766222

関連ノート

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