DL-Carnitine → Cyclohexyl acetyl carnitine chloride

HRID 35373

反応式

HRID 35373 の反応式
[CH3:1][N+:2]([CH2:5][CH:6]([OH:11])[CH2:7][C:8]([O-:10])=[O:9])([CH3:4])[CH3:3].[CH:12]1(CC([Cl:21])=O)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[CH2:22]([O:24]CC)[CH3:23]>FC(F)(F)C(O)=O>[CH:12]1([CH:5]([N+:2]([CH3:3])([CH3:4])[CH3:1])[C:6]([C:22](=[O:24])[CH3:23])([CH2:7][C:8](=[O:10])[O-:9])[OH:11])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[Cl-:21]

参加物

5

反応物 3

HCID 288DL-CarnitineHCID 3283Diethyl EtherHCID 2757989Cyclohexylacetyl chloride

生成物 1

HCID 131715698Cyclohexyl acetyl carnitine chloride

試薬・触媒・溶媒 1

HCID 6422Trifluoroacetic acid溶媒

実験手順

Carnitine chloride (2.97 g; 0.01 moles) was dissolved in trifluoro acetic acid (10 cc). To this solution was added cyclohexyl acetyl chloride (0.01 moles) prepared as previously disclosed and the resulting mixture was kept under stirring for 48 hours. Ethyl ether was then added and the resulting mixture was kept under stirring for 0.5 hours at 0° C. A precipitate was obtained, which was filtered off and dried under vacuum.

後処理

  1. customprepared
  2. stirringunder stirring for 0.5 hours at 0° C
  3. customA precipitate was obtained
  4. filtrationwhich was filtered off
  5. customdried under vacuum

出典と根拠

ORDレコード
ord-ccb56ca24b4b4916a6432cb595293d2a
出典データセット
uspto-grants-1988_08
特許番号
US04766222

関連ノート

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