Cadaverine → N-(5-Aminopentyl)benzamide
反応式
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH2:7].[C:8](N)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][C:8](=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1参加物
3
実験手順
Under an argon atmosphere, 1,5-diaminopentane (25 g, 0.24 mol) and benzamide (9.9 g, 0.081 mol) were combined and heated at reflux overnight. The reaction mixture was concentrated under vacuum to remove the excess diamine. The residue was distilled at about 210° C. at 12 torr (16×102 pascals) to provide 11.8 g of N-(5-aminopentyl)benzamide as a colorless oil.
後処理
- temperatureheated
- temperatureat reflux overnight
- concentrationThe reaction mixture was concentrated under vacuum
- customto remove the excess diamine
- distillationThe residue was distilled at about 210° C. at 12 torr (16×102 pascals)
出典と根拠
- ORDレコード
- ord-b381b192013040f686acf978ecc3b618
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06756382B2
反応ノート
読み込み中…