Furan → Phosphonic acid, 2-furanyl-, diethyl ester
反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[Li]CCCC.[P:11](Cl)([O:16][CH2:17][CH3:18])([O:13][CH2:14][CH3:15])=[O:12]>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[P:11]([O:16][CH2:17][CH3:18])(=[O:12])[O:13][CH2:14][CH3:15]参加物
5
実験手順
A solution of furan (1 mmole) in diethyl ether was treated with TMEDA (N,N,N′N′-tetramethylethylenediamine) (1 mmole) and nBuLi (2 mmole) at −78° C. for 0.5 h. Diethyl chlorophosphate (1.2 mmole) was added to the reaction mixture and stirred for another hour. Extraction and distillation gave diethyl 2-furanphosphonate as a clear oil.
後処理
- extractionExtraction and distillation
出典と根拠
- ORDレコード
- ord-2cef6820965a4d6e82d57e609f00f9cd
- 出典データセット
- uspto-grants-2004_06
- 特許番号
- US06756360B1
反応ノート
読み込み中…