Hydrochloric Acid → Cyanuric chloride

HRID 354262ノート

反応式

HRID 354262 の反応式
[N:1]1[C:8]([Cl:9])=[N:7][C:5]([Cl:6])=[N:4][C:2]=1[Cl:3].[CH3:10][CH:11](O)[CH2:12][CH2:13][CH3:14].[S:16]([Cl:19])([Cl:18])=[O:17].[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.Cl>[Cl-].[Zn+2].[Cl-].Cl>[Cl:3][CH:11]([CH2:12][CH2:13][CH3:14])[CH3:10].[S:16]([Cl:19])([Cl:18])=[O:17].[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[N:1]1[C:8]([Cl:9])=[N:7][C:5]([Cl:6])=[N:4][C:2]=1[Cl:3]

参加物

8

反応物 4

HCID 313Hydrochloric AcidHCID 7954Cyanuric chloride2 回HCID 223862-PentanolHCID 85801105Thionyl chloride pyridine

生成物 3

HCID 7954Cyanuric chlorideHCID 122452-ChloropentaneHCID 85801105Thionyl chloride pyridine

試薬・触媒・溶媒 1

HCID 21263579ZINC chloride hydrogen chloride触媒

実験手順

Methods of preparing isomerically pure alkyl chlorides are known and described in the literature. S. R. Sandler, J. Org. Chem. 35, 3967 (1970), describes the conversion of primary, secondary and tertiary alcohols into alkyl chloride compounds by reacting the alcohols with an excess of cyanuric chloride under anhydrous conditions. Furthermore, on page 3968 of the text, the reaction of 2-pentanol with cyanuric chloride, zinc chloride/hydrogen chloride, thionyl chloride/pyridine and with hydrogen chloride is described. Isomerically pure 2-chloro-pentane is obtained in a yield of 48% in the reaction with thionyl chloride/pyridine and in a yield of 57% in the reaction with cyanuric chloride alone.

出典と根拠

ORDレコード
ord-40a752ee8b0e448f9a739b393706efb6
出典データセット
uspto-grants-2004_06
特許番号
US06756513B2

反応ノート

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