Acetone → Bisphenol A

HRID 35433

反応式

HRID 35433 の反応式
CC(C)=[O:3].[C:5]1([OH:11])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.Cl[Si](C)(C)C.[CH2:17](S)[CH2:18][CH2:19]C.Cl[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[OH:11][C:5]1[CH:10]=[CH:9][C:8]([C:18]([C:23]2[CH:28]=[CH:27][C:26]([OH:3])=[CH:25][CH:24]=2)([CH3:19])[CH3:17])=[CH:7][CH:6]=1

参加物

6

反応物 5

HCID 180AcetoneHCID 996PhenolHCID 6397ChlorotrimethylsilaneHCID 7964ChlorobenzeneHCID 8012Butanethiol

生成物 1

HCID 6623Bisphenol A収率 83%

反応条件

温度
55 °C

実験手順

Into a 250-millimiter 3-necked round-bottomed flask was charged a mixture of 11.6 grams (0.20 mole) of acetone, 75 grams (0.80 mole) of phenol, 22 grams (0.20 mole) of chlorotrimethyl silane, and 0.10 gram of butanethiol. The resulting mixture was stirred mechanically and heated at 55° C. under a nitrogen atmosphere for 3 hours. On completion of the reaction, the reaction mixture was cooled to room temperature and filtered. The solid product resulting was slurried up in chlorobenzene, filtered and washed twice with chlorobenzene. Purification by recrystallization from methanol and water afforded bisphenol A with a purity of 99.5 percent in a 83 percent yield.

後処理

  1. additionInto a 250-millimiter 3-necked round-bottomed flask was charged
  2. customOn completion of the reaction
  3. temperaturethe reaction mixture was cooled to room temperature
  4. filtrationfiltered
  5. customThe solid product resulting
  6. filtrationfiltered
  7. washwashed twice with chlorobenzene
  8. customPurification
  9. customby recrystallization from methanol and water

出典と根拠

ORDレコード
ord-f5c8b7b2cd3e4b34bbb92e3ac7d465ad
出典データセット
uspto-grants-1988_08
特許番号
US04766255

関連ノート

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