Water → HCID 13135248、化合物
反応式
[C:1]([C:3]1[C:4]([CH3:13])=[C:5]([C:9]([CH3:12])=[CH:10][CH:11]=1)[C:6](O)=[O:7])#[N:2].B.O.C(=O)([O-])[O-].[K+].[K+]>O1CCCC1>[C:1]([C:3]1[C:4]([CH3:13])=[C:5]([CH2:6][OH:7])[C:9]([CH3:12])=[CH:10][CH:11]=1)#[N:2]参加物
6
実験手順
A solution of 3-cyano-2,6-dimethylbenzoic acid (8.11 grams, 0.049 mole) in tetrahydrofuran (100 ml) was cooled to 0°. Borane (48.7 grams, 0.049 mole) in tetrahydrofuran was added dropwise over a 20 minute period. The mixture was allowed to come to room temperature, and water was added. Potassium carbonate was added to separate the layers. The aqueous layer was extracted with diethyl ether. The extract was added to the organic phase, which was dried over magnesium sulfate, filtered, and the solvent evaporated to give (3-cyano-2,6-dimethylphenyl)methanol (2.93 grams).
後処理
- customto come to room temperature
- customto separate the layers
- extractionThe aqueous layer was extracted with diethyl ether
- additionThe extract was added to the organic phase, which
- dry with materialwas dried over magnesium sulfate
- filtrationfiltered
- customthe solvent evaporated
出典と根拠
- ORDレコード
- ord-b4710c02690841ae94fc02b6b2f138f5
- 出典データセット
- uspto-grants-1983_03
- 特許番号
- US04375476
反応ノート
読み込み中…