関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | 2-Aminobenzonitrile | HCID 72913 | — |
| 生成物 | 4-Aminoquinazoline | HCID 84759 | — |
反応手順
A mixture of o-aminobenzonitrile (22.58 g) and formamide (96 ml) was refluxed for 2 hours at 220° C. After the resultant mixture was cooled to ambient temperature, precipitated crystals were separated by filtration, washed twice with a small volume of water and dried under reduced pressure to give crystalline 4-aminoquinazoline (17.0 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04377580 |
|---|
| 出典データセット | uspto-grants-1983_03 |
|---|
| ORD ID | ord-5deb0920a34d494fb43b1e7b80c6165f |
|---|
| 出典メモ | uspto-grants-1983_03 |
|---|
