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Sodium hydride → 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- | HCID 84657 | — |
| 反応物 | Methyl 11-bromoundecanoate | HCID 223913 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester | HCID 12961187 | — |
反応手順
The product is produced as described in example 1 from 1.3 g. of NaH (80% suspension in mineral oil), 10 g. of 1-phenylbenzimidazolin-2-one, 200 cc. of DMF, 13.3 g. of 11-bromoundecanoic acid methyl ester and 1.3 g. of NaJ. Eluant in chromatographic purification: hexane/ethylacetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04377695 |
| 出典データセット | uspto-grants-1983_03 |
| ORD ID | ord-133a1494065746b1ad3399c84cba163e |
| 出典メモ | uspto-grants-1983_03 |