Potassium Carbonate → 3-(Benzyloxy)piperidine

HRID 355125ノート

反応式

HRID 355125 の反応式
C([N:4]1[CH2:9][CH2:8][CH2:7][CH:6]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:5]1)(=O)C.[OH-].[Na+].C(=O)([O-])[O-].[K+].[K+]>O>[CH2:11]([O:10][CH:6]1[CH2:7][CH2:8][CH2:9][NH:4][CH2:5]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 205061191-Acetyl-3-benzyloxypiperidine

生成物 1

HCID 199606043-(Benzyloxy)piperidine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-Acetyl-3-benzyloxypiperidine (0.043 mole), sodium hydroxide (0.086 mole) and water (30 ml.) are combined and refluxed for 24 hours. The reaction mixture is saturated with potassium carbonate and extracted three times with ether. The ether is removed by evaporation and the yellow oil is distilled at 92°-94° C. (0.3 mm Hg.).

後処理

  1. temperaturerefluxed for 24 hours
  2. extractionextracted three times with ether
  3. customThe ether is removed by evaporation
  4. distillationthe yellow oil is distilled at 92°-94° C. (0.3 mm Hg.)

出典と根拠

ORDレコード
ord-62c29e7729194ec8bec6da8df5c69f62
出典データセット
uspto-grants-1983_03
特許番号
US04377521

反応ノート

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