反応式
BrC[CH2:3][CH2:4][CH:5]([CH3:11])[CH:6]([CH3:10])[C:7]([OH:9])=[O:8].C(O)(=O)C(C)C.[Cl:18]CCCCl>>[Cl:18][CH2:3][CH2:4][CH:5]([CH3:11])[CH:6]([CH3:10])[C:7]([OH:9])=[O:8]参加物
4
実験手順
The title compound was prepared as described for 6-bromo-2,3-dimethylhexanoic acid from isobutyric acid (9.67 g, 109.8 mmol), and 1,3-dichloropropane (37.2 g, 329.2 mmol). The product was purified by flash chromatography (CHCl3) to provide the acid (0.9 g, 5%) as a oil, HRMS (M+Li)+ calcd for C7H13O2ClLi 171.0764, found 171.0766.
後処理
- customThe product was purified by flash chromatography (CHCl3)
出典と根拠
- ORDレコード
- ord-9dc23f2b8639435eb4cb47e15da30ebc
- 出典データセット
- uspto-grants-1998_11
- 特許番号
- US05830888
関連ノート
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