Dimethylformamide → 4-(3-Dimethylaminophenoxy)butyronitrile
反応式
[CH3:1][N:2]([CH3:10])[C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.C(=O)([O-])[O-].[K+].[K+].CN(C)C=O.Br[CH2:23][CH2:24][CH2:25][C:26]#[N:27]>O>[CH3:1][N:2]([CH3:10])[C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[O:9][CH2:23][CH2:24][CH2:25][C:26]#[N:27]参加物
6
実験手順
A suspension of 3-dimethylaminophenol (5 g), potassium carbonate (10.05 g) and dimethylformamide (85 ml) was stirred at room temperature for 5 hours. 4-Bromobutyronitrile (7.3 ml) was added and the suspension stirred for 17 hours. The reaction mixture was poured into water and extracted with ethyl acetate. The extracts were washed with water, dried and the solvent removed to yield 4-(3-dimethylaminophenoxy)butyronitrile.
後処理
- stirringthe suspension stirred for 17 hours
- extractionextracted with ethyl acetate
- washThe extracts were washed with water
- customdried
- customthe solvent removed
出典と根拠
- ORDレコード
- ord-7c7eb924af47428b8286be45c1256f2f
- 出典データセット
- uspto-grants-1988_08
- 特許番号
- US04767769
反応ノート
読み込み中…