Methyl iodide → HCID 18630005、化合物

反応式

[CH2:1]([N:3]([CH2:16][O:17][CH3:18])[C:4](=[O:15])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Si:11]([CH3:14])([CH3:13])[CH3:12])[CH3:2].[CH3:19]I>>[CH2:1]([N:3]([CH2:16][O:17][CH3:18])[C:4](=[O:15])[C:5]1[C:6]([Si:11]([CH3:13])([CH3:12])[CH3:14])=[CH:7][CH:8]=[CH:9][C:10]=1[CH3:19])[CH3:2]

参加物

反応物 2

HCID 6328Methyl iodide

HCID 18630303HCID 18630303、化合物

生成物 1

HCID 18630005HCID 18630005、化合物

実験手順

The compound of Example 50 (1.33 g, 5.0 mmol) and MeI (2.8 g, 20 mmol) were combined according to General Method B. The resulting reaction was partitioned between ethyl acetate and sat aq NaHCO3. The organic phase was washed with brine, dried (MgSO4), and concentrated to afford a quantitative yield of the title compound as an oil.

後処理

customThe resulting reaction
customwas partitioned between ethyl acetate
washThe organic phase was washed with brine
dry with materialdried (MgSO4)
concentrationconcentrated

出典と根拠

ORDレコード: ord-9b38a03cbc0c474799b145ce7f101ae0
出典データセット: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05834447

反応ノート

読み込み中…

参加物