Dimethylformamide → Bis(4-ethoxyphenyl) disulfide

HRID 356843

反応式

HRID 356843 の反応式
[C:1](=[O:4])([O-])[O-].[K+].[K+].[CH2:7](I)[CH3:8].O[C:11]1[CH:16]=[CH:15][C:14]([S:17][S:18][C:19]2[CH:24]=[CH:23][C:22]([OH:25])=[CH:21][CH:20]=2)=[CH:13][CH:12]=1.[CH3:26]N(C=O)C>>[CH2:7]([O:25][C:22]1[CH:23]=[CH:24][C:19]([S:18][S:17][C:14]2[CH:15]=[CH:16][C:11]([O:4][CH2:1][CH3:26])=[CH:12][CH:13]=2)=[CH:20][CH:21]=1)[CH3:8]

参加物

5

反応物 4

HCID 6228DimethylformamideHCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 2806654-[(4-Hydroxyphenyl)disulfanyl]phenol

生成物 1

HCID 580750Bis(4-ethoxyphenyl) disulfide収率 82%

反応条件

温度
70 °C

実験手順

Potassium carbonate (2.2 g) and ethyl iodide (4.3 g) were added to a solution of bis(p-hydroxyphenyl)disulfide (2.0 g) in DMF (20 ml), and the mixture was stirred at 70° C. for 16 hours and poured into ice water (100 ml). The mixture was extracted with hexane (500 ml) and concentrated to give bis(p-ethoxyphenyl)disulfide (1.8 g, 82%).

後処理

  1. extractionThe mixture was extracted with hexane (500 ml)
  2. concentrationconcentrated

出典と根拠

ORDレコード
ord-ef6f3fef6e4248d99d5f10bd8e61ed3e
出典データセット
uspto-grants-1998_11
特許番号
US05840716

関連ノート

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