5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene → (3S)-3-Methylheptan-1-OL

HRID 35723ノート

反応式

HRID 35723 の反応式
[CH3:1][C@H:2]([CH2:7][CH2:8][O:9][Si](C(C)(C)C)(C)C)[CH2:3][CH:4]=[CH:5][CH3:6].[H][H]>[OH-].[OH-].[Pd+2].CO>[CH3:1][C@@H:2]([CH2:3][CH2:4][CH2:5][CH3:6])[CH2:7][CH2:8][OH:9]

参加物

5

反応物 2

HCID 537803775-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-hepteneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 12490717(3S)-3-Methylheptan-1-OL

試薬・触媒・溶媒 2

HCID 9942167Palladium hydroxide触媒HCID 887Methanol溶媒

実験手順

To a solution of 74.8 g. of 5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene in 500 ml. of methanol was added 7.5 g. of 10% palladium hydroxide on carbon and the mixture shaken in a hydrogen atmosphere for 1.5 hours at 50 psi. The catalyst was filtered and the solvent removed under vacuum, 30 g.

後処理

  1. filtrationThe catalyst was filtered
  2. customthe solvent removed under vacuum, 30 g

出典と根拠

ORDレコード
ord-01daf8a69ff143439ee15aa2712ff87a
出典データセット
uspto-grants-1988_08
特許番号
US04767743

反応ノート

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