Methyl iodide → 4-(3-Acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide

HRID 357496

反応式

HRID 357496 の反応式
[C:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11]2[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH2:18])[N:12]=2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].[CH3:19][I:20]>CC(C)=O>[I-:20].[C:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11]2[CH:16]=[C:15]([CH3:17])[N+:14]([CH3:19])=[C:13]([NH2:18])[N:12]=2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 133110Cni H1594

生成物 1

HCID 120932594-(3-Acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Compound No. 14: 4-(3-acetylphenyl)amino-2-amino-6-methylpyrimidine, Compound No. 15, (0.968 g) was suspended in acetone (5 mL) containing methyl iodide (2 mL) was heated at reflux for 48 hr. Filtration after cooling gave 0.657 g of 4-(3-acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide as a white powder, mp 238°-40° C.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 48 hr
  3. filtrationFiltration
  4. temperatureafter cooling

出典と根拠

ORDレコード
ord-6e1482d67e4c4a03b670aef144a7d39a
出典データセット
uspto-grants-1998_11
特許番号
US05840893

関連ノート

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