Methyl Isocyanate → N,2-Dimethyl-2,3-dihydro-1H-indole-1-carboxamide
反応式
[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3]1.[CH3:11][N:12]=[C:13]=[O:14]>C1(C)C=CC=CC=1>[CH3:11][NH:12][C:13]([N:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH2:10][CH:2]1[CH3:1])=[O:14]参加物
4
実験手順
1 mole of 2-methylindoline is dissolved in 300 ml of toluene and 1 mole of methyl isocyanate is added, the temperature not rising above 25° C. The mixture is left to stand for 1 day and the resulting precipitate is then filtered off. N-Methylaminocarbonyl-2-methylindoline with a melting point of 158°-160° C. is obtained. Yield: 89% of theory.
後処理
- customrising above 25° C
- waitThe mixture is left
- filtrationthe resulting precipitate is then filtered off
出典と根拠
- ORDレコード
- ord-301534f4b203478c9dc009a74deb5d9e
- 出典データセット
- uspto-grants-1984_08
- 特許番号
- US04466964
反応ノート
読み込み中…