Thionyl Chloride → 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride
反応式
[OH:1][C:2]1[C:3]([OH:16])=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([C:12](O)=[O:13])=[CH:7][C:6]=2[CH:15]=1.S(Cl)([Cl:19])=O>CN(C)C=O>[OH:1][C:2]1[C:3]([OH:16])=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([C:12]([Cl:19])=[O:13])=[CH:7][C:6]=2[CH:15]=1参加物
4
実験手順
A mixture of 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid (110 mg), thionyl chloride (5 mL), and dimethylformamide (one drop) was stirred for 2 hours at room temperature. The excess thionyl chloride was distilled off in vacuo. Benzene (20 mL) was added, followed by vacuum distillation and vacuum drying, to yield 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride.
後処理
- distillationThe excess thionyl chloride was distilled off in vacuo
- additionBenzene (20 mL) was added
- distillationfollowed by vacuum distillation and vacuum
- customdrying
出典と根拠
- ORDレコード
- ord-863a20bb54bf471d93e5e18abcfbc03b
- 出典データセット
- uspto-grants-1984_08
- 特許番号
- US04468394
反応ノート
読み込み中…