Hydrochloric Acid → 6-((Phenylsulphonyl)amino)hexanoic acid
反応式
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18].Cl>[OH-].[Na+]>[C:1]1([S:7]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
5
実験手順
Benzenesulphonyl chloride (10 ml) was added to a stirred solution of 6-aminocaproic acid (8.8 g) in 10% sodium hydroxide solution (50 ml) over 30 minutes. The solution was stirred for 1 hour, acidified with dilute hydrochloric acid and the precipitate was collected by filtration. Recrystallisation from chloroform yielded 6-(benzenesulphonamido)hexanoic acid (10.5 g) as white prisms. m.p. 119°-120° C.
後処理
- filtrationthe precipitate was collected by filtration
- customRecrystallisation from chloroform
出典と根拠
- ORDレコード
- ord-22843f89e6f0414196a01b312c3696f5
- 出典データセット
- uspto-grants-1991_03
- 特許番号
- US04997847
反応ノート
読み込み中…