Anthranilamide → N-[(2-carbamoylphenyl)carbamothioyl]-3-methylbenzamide

HRID 359529

反応式

HRID 359529 の反応式
[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[CH3:11][C:12]1[CH:13]=[C:14]([CH:20]=[CH:21][CH:22]=1)[C:15]([N:17]=[C:18]=[S:19])=[O:16]>CCOCC>[NH2:6][C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[NH:1][C:18](=[S:19])[NH:17][C:15](=[O:16])[C:14]1[CH:20]=[CH:21][CH:22]=[C:12]([CH3:11])[CH:13]=1)=[O:5]

参加物

4

反応物 2

HCID 6942AnthranilamideHCID 1413973-Methylbenzoyl isothiocyanate

生成物 1

HCID 667545N-[(2-carbamoylphenyl)carbamothioyl]-3-methylbenzamide収率 89.3%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a stirred mixture of 7.2 g of 2-aminobenzamide and 200 ml of ether was added dropwise, a solution of 10 g of 3-methylbenzoyl isothiocyanate over 10 minutes. After 48 hours, the solid was collected, giving 14.8 g of the desired product as grey crystals, mp 194°-196° (dec.).

後処理

  1. additionwas added dropwise
  2. customthe solid was collected

出典と根拠

ORDレコード
ord-0d79b3cbfe21472dbe9de27f6fa957f8
出典データセット
uspto-grants-1991_03
特許番号
US05001157

関連ノート

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