Indole-3-pyruvic acid → HCID 12457675、化合物
反応式
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][C:11](=[O:15])[C:12]([OH:14])=[O:13])=[CH:2]1.[CH2:16]1CCN2C(=NCCC2)C[CH2:17]1.C(Br)C>C1C=CC=CC=1>[CH2:16]([O:13][C:12](=[O:14])[C:11]([CH2:10][C:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH:1][CH:2]=1)=[O:15])[CH3:17]参加物
5
実験手順
Following the same method as previously described, 1,0 g 3-indole-pyruvic acid were reacted with 1,5 ml DBU and 790 microliters ethylbromide. In this case the benzene solution appeared red orange. After flash chromatography purification the ethyl ester was obtained with a yield of about 70%.
後処理
- customAfter flash chromatography purification the ethyl ester
- customwas obtained with a yield of about 70%
出典と根拠
- ORDレコード
- ord-b950a389228e4d7da502945220a05509
- 出典データセット
- uspto-grants-1991_03
- 特許番号
- US05002963
反応ノート
読み込み中…