化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloroethyl chloroformate → 1-Chloroethyl N-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)]propyl-N-methylcarbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloroethyl chloroformate | HCID 12305 | — |
| 反応物 | Desipramine Hydrochloride | HCID 65327 | — |
| 生成物 | 1-Chloroethyl N-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)]propyl-N-methylcarbamate | HCID 15679987 | 86% |
反応手順
Following the general procedure of Example 50, but using 1.5 g (0.005 mol) of desipramine hydrochloride and 0.86 g (0.006 mol) chloroethyl chloroformate and carrying out the reaction at 5°-10° C. for 2 hours, gave 1.6 g (86%) of the title compound as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05002935 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-1f68f471672b475e971807d6b8252c2f |
| 出典メモ | uspto-grants-1991_03 |