Nitric Acid → 2-Amino-3,5-dinitropyridine

HRID 36106

反応式

HRID 36106 の反応式
[NH2:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[N+:11]([O-])([OH:13])=[O:12]>OS(O)(=O)=O>[NH2:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 944Nitric AcidHCID 778873-Nitropyridin-2-ylamine

生成物 1

HCID 5043402-Amino-3,5-dinitropyridine

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

To a stirred solution of 2-amino-3-nitropyridine in conc. H2SO4 (50 mL) at 0° C. was added HNO3 (3.10 mL, d=1.49) dropwise over 10 min. The mixture was warmed to r.t. for 20 min then heated to 50° C. for 90 min. The reaction mixture was cooled and poured into 400 g of ice. The resulting precipitate was filtered and air dried to give 10.3 g of 2-amino-3,5-dinitropyridine as a yellow solid.

後処理

  1. temperaturethen heated to 50° C. for 90 min
  2. temperatureThe reaction mixture was cooled
  3. filtrationThe resulting precipitate was filtered
  4. customair dried

出典と根拠

ORDレコード
ord-4b811c4440df4bf9ab817db4d5ed5ede
出典データセット
uspto-grants-1995_05
特許番号
US05412097

関連ノート

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