(1,4-Dibenzyl-1,4-diazepan-6-yl)methanol → (1,4-Diazepan-6-yl)methanol
反応式
C([N:8]1[CH2:14][CH:13]([CH2:15][OH:16])[CH2:12][N:11](CC2C=CC=CC=2)[CH2:10][CH2:9]1)C1C=CC=CC=1>CO.[Pd]>[NH:8]1[CH2:14][CH:13]([CH2:15][OH:16])[CH2:12][NH:11][CH2:10][CH2:9]1参加物
4
実験手順
2.26 g (7.3 mmol) of (1,4-dibenzyl-[1,4]-diazepan-6-yl)-methanol are dissolved in 150 ml of methanol and hydrogenated at room temperature and normal pressure in the presence of 0.5 g of 10% palladium on activated charcoal. [1,4]-Diazepan-6-yl-methanol is obtained in the form of a light yellow oil by filtration and concentration of the filtrate.
出典と根拠
- ORDレコード
- ord-7523249cc78043c3b0d631d3c5c90302
- 出典データセット
- uspto-grants-1999_02
- 特許番号
- US05866562
反応ノート
読み込み中…