関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)- | HCID 36566 | — |
| 生成物 | 1-Ethyl-5-nitro-indoline | HCID 23499145 | 109.4% |
反応手順
1-Acetyl-5-nitro-indoline (1.00 g, 4.85 mmol) was added to borane-THF complex 1M, 10 mL, 10 mmol). The mixture was heated at reflux for 4 h. With ice-water bath cooling, the mixture was slowly reated with 6N HCl (4 mL). Then the mixture was heated at 50° C. for 1 h. The organic solvent was evaporated off and the resulting suspension was filtered to give an orange solid (1.02 g) which was washed with water: mp 97°-98° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05866579 |
|---|
| 出典データセット | uspto-grants-1999_02 |
|---|
| ORD ID | ord-cae08d09cb174c56a3c433fba5933db8 |
|---|
| 出典メモ | uspto-grants-1999_02 |
|---|
