N-heptylacetamide → 1-Heptanamine, N-ethyl-

HRID 36145

反応式

HRID 36145 の反応式
[CH2:1]([NH:8][C:9](=O)[CH3:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[H-].[Al+3].[Li+].[H-].[H-].[H-].O.[OH-].[Na+]>C(OCC)C>[CH2:1]([NH:8][CH2:9][CH3:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

参加物

5

反応物 3

HCID 347488N-heptylacetamideHCID 21226445Aluminium lithium hydrideHCID 23719242Sodium hydroxide--water (1/1/1)

生成物 1

HCID 480381-Heptanamine, N-ethyl-

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of a solution of 5.5 gms of the N-heptylacetamide in 150 ml of diethyl ether and 3.99 gms of lithium aluminum hydride are stirred at room temperature for 18 hours. The reaction mixture is then worked up with H2O/NaOH by the Fieser method, following which the organic layer is dried over MgSO4, filtered, and concentrated under vacuum to give N-heptyl-N-ethylamine.

後処理

  1. dry with materialis dried over MgSO4
  2. filtrationfiltered
  3. concentrationconcentrated under vacuum

出典と根拠

ORDレコード
ord-f3528eb525984558858b648e2ac6c3f7
出典データセット
uspto-grants-1995_05
特許番号
US05412137

関連ノート

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