化工社化工社 化学情報印刷レポート · 研究参考用
Water → Propionitrile, 3-(p-chlorophenoxy)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 4-Chlorophenol | HCID 4684 | — |
| 反応物 | Acrylonitrile | HCID 7855 | — |
| 反応物 | Benzyltrimethylammonium hydroxide | HCID 66854 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Propionitrile, 3-(p-chlorophenoxy)- | HCID 96550 | — |
反応手順
A mixture of p-chlorophenol (25 g), acrylonitrile (30 ml) and a solution of benzyltrimethylammonium hydroxide (8 ml of a 40 wt % solution in methanol) were heated at reflux over the weekend. The reaction mixture was poured into water and extracted with ethyl acetate. The ethyl acetate extract was dried and evaporated to give 3-(4-chlorophenoxy)propionitrile.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05866611 |
| 出典データセット | uspto-grants-1999_02 |
| ORD ID | ord-525446a4cf4c4e54862c339880ef50f7 |
| 出典メモ | uspto-grants-1999_02 |