1,3,5-Triazine → HCID 178436090、化合物

HRID 362449

反応式

HRID 362449 の反応式
[CH3:1][C:2]1[CH2:3][C:4](=[O:16])[N:5]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=2)[N:6]=1.[N:17]1[CH:22]=NC=N[CH:18]=1.[CH2:23]([C:25]1C=[CH:30][CH:29]=[CH:28][C:26]=1N)[CH3:24]>C(O)C>[CH2:29]([C:28]1[CH:26]=[CH:25][CH:23]=[CH:24][C:18]=1[NH:17][CH:22]=[C:3]1[C:2]([CH3:1])=[N:6][N:5]([C:7]2[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=2)[C:4]1=[O:16])[CH3:30]

参加物

5

反応物 3

HCID 92621,3,5-TriazineHCID 113572-EthylanilineHCID 808163H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-(4-nitrophenyl)-

生成物 1

HCID 178436090HCID 178436090、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1 g of 5-methyl-2-(4-nitrophenyl)-2,4-dihydro-3-pyrazolone, 190 mg of 1,3,5-triazine and 0.74 ml of 2-ethylaniline are heated under reflux in 50 ml of ethanol for 4 days. The solvent is evaporated off in vacuo, and the crude reaction product obtained in this way is purified by chromatography on silica gel with a solvent mixture consisting of dichloromethane and methanol mixed in the ratio of 97:3 as eluent.

後処理

  1. customThe solvent is evaporated off in vacuo
  2. customthe crude reaction product
  3. customobtained in this way
  4. customis purified by chromatography on silica gel with a solvent mixture
  5. additionmixed in the ratio of 97:3 as eluent

出典と根拠

ORDレコード
ord-97d23a9c2b7e45e483b297605ab01bb9
出典データセット
uspto-grants-1999_02
特許番号
US05869516

関連ノート

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