Water → 6-Phenylnicotinic acid

HRID 363184

反応式

HRID 363184 の反応式
[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([C:13]([OH:15])=[O:20])=[CH:9][N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 962WaterHCID 474675-Methyl-2-phenylpyridineHCID 516875Potassium Permanganate

生成物 1

HCID 1201186-Phenylnicotinic acid

実験手順

A suspension of 2-phenyl-5-methyl pyridine (1.03 g, 6.09 mmol) and potassium permanganate (2.89 g, 18.3 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

後処理

  1. temperatureat reflux for 2 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (1 mL) was added to the colourless filtrate
  5. filtrationthe product was collected as a white solid by filtration

出典と根拠

ORDレコード
ord-6e644e5ebedd4852bf22e76bd7adb84c
出典データセット
uspto-grants-1999_02
特許番号
US05872136

関連ノート

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