Water → 5-phenylpyridine-2-carboxylic Acid

HRID 363187ノート

反応式

HRID 363187 の反応式
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:8]=[N:9][C:10]([C:13]([OH:15])=[O:20])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 962WaterHCID 767442-Methyl-5-phenylpyridineHCID 516875Potassium Permanganate

生成物 1

HCID 27628705-phenylpyridine-2-carboxylic Acid

実験手順

A suspension of 3-phenyl-6-methyl pyridine (1.99 g, 11.78 mmol) and potassium permanganate (7.65, 48.6 mmol), in water (50 mL) was heated at reflux for 16 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (2 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

後処理

  1. temperatureat reflux for 16 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (2 mL) was added to the colourless filtrate
  5. filtrationthe product was collected as a white solid by filtration

出典と根拠

ORDレコード
ord-343691b2d04c48aca1c08a10cca1ee35
出典データセット
uspto-grants-1999_02
特許番号
US05872136

反応ノート

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