Water → 5-phenylpyridine-2-carboxylic Acid
反応式
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:8]=[N:9][C:10]([C:13]([OH:15])=[O:20])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
4
実験手順
A suspension of 3-phenyl-6-methyl pyridine (1.99 g, 11.78 mmol) and potassium permanganate (7.65, 48.6 mmol), in water (50 mL) was heated at reflux for 16 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (2 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.
後処理
- temperatureat reflux for 16 hours
- filtrationfiltered through celite
- customto remove the solids
- additionAcetic acid (2 mL) was added to the colourless filtrate
- filtrationthe product was collected as a white solid by filtration
出典と根拠
- ORDレコード
- ord-343691b2d04c48aca1c08a10cca1ee35
- 出典データセット
- uspto-grants-1999_02
- 特許番号
- US05872136
反応ノート
読み込み中…