Hydrochloric Acid → 5-Methoxy-2,4-dinitrophenol

HRID 36435

反応式

HRID 36435 の反応式
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[C:4](Cl)[CH:3]=1.[CH3:15][OH:16].[OH-:17].[Na+].Cl>O>[CH3:15][O:16][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[C:4]([OH:17])[CH:3]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 14798Sodium HydroxideHCID 772861,3-Dichloro-4,6-dinitrobenzene

生成物 1

HCID 2667955-Methoxy-2,4-dinitrophenol収率 95%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
65 °C

実験手順

A 1 liter (L) round-bottom flask equipped with a mechanical stirrer and a reflux condenser is charged with 23.7 grams (g) of 1,3-dichloro-4,6-dinitrobenzene, 100 milliliters (mL) of methanol, 200 mL of water and 15 grams of sodium hydroxide and heated to approximately 65° C. for about 8 hours. The reaction mixture is then poured into 0° C. aqueous hydrochloric acid, isolated by filtration and air-dried. The theoretical yield of 5-methoxy-2,4-dinitrophenol, a monoether of dinitroresorcinol, is 21.4 g, and the dry weight yield is 20.5 g which gives an overall 95% yield of 5-methoxy-2,4-dinitrophenol.

後処理

  1. customisolated by filtration
  2. customair-dried

出典と根拠

ORDレコード
ord-c68d4a632ee7489e9e01bb6b4011b5c9
出典データセット
uspto-grants-1995_05
特許番号
US05414130

関連ノート

読み込み中…