N-(2-Acetylphenyl)acetamide → HCID 54331422、化合物

HRID 364852

反応式

HRID 364852 の反応式
[O:1]=[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:13])[CH3:12])[CH3:3].CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>C1(C)C=CC=CC=1>[CH3:16][N:17]([CH3:19])[CH:18]=[CH:3][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:13])[CH3:12])=[O:1]

参加物

4

反応物 2

HCID 21306N-(2-Acetylphenyl)acetamideHCID 78373Dimethylformamide dimethyl acetal

生成物 1

HCID 54331422HCID 54331422、化合物収率 63.6%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

A suspension of 48 g of N-[2-(1-oxo-1-ethanyl)phenyl]acetamide and 38 g of N,N-dimethylformamide dimethyl acetal in 150 ml of toluene was heated at reflux for about 16 hours, then concentrated in vacuo to a solid. The solid was recrystallized from 1-chlorobutane to yield 40 g of the title compound; m.p. 90°-95° C.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for about 16 hours
  3. concentrationconcentrated in vacuo to a solid
  4. customThe solid was recrystallized from 1-chlorobutane

出典と根拠

ORDレコード
ord-93ec883c9ccb4b28914aad0f2c2c7668
出典データセット
uspto-grants-1986_08
特許番号
US04606755

関連ノート

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