N-(2-Acetylphenyl)acetamide → N-[2-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]acetamide
反応式
[O:1]=[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:13])[CH3:12])[CH3:3].CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>C1(C)C=CC=CC=1>[CH3:16][N:17]([CH3:19])[CH:18]=[CH:3][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:13])[CH3:12])=[O:1]参加物
4
実験手順
A suspension of 48 g of N-[2-(1-oxo-1-ethanyl)phenyl]acetamide and 38 g of N,N-dimethylformamide dimethyl acetal in 150 ml of toluene was heated at reflux for about 16 hours, then concentrated in vacuo to a solid. The solid was recrystallized from 1-chlorobutane to yield 40 g of the title compound; m.p. 90°-95° C.
後処理
- temperaturewas heated
- temperatureat reflux for about 16 hours
- concentrationconcentrated in vacuo to a solid
- customThe solid was recrystallized from 1-chlorobutane
出典と根拠
- ORDレコード
- ord-93ec883c9ccb4b28914aad0f2c2c7668
- 出典データセット
- uspto-grants-1986_08
- 特許番号
- US04606755
反応ノート
読み込み中…